Endocrine Abstracts

Aim: Studying of influence of various doses of cabergoline in dynamics of 6, 12 and 24 months of treatment on level of blood serum soluble apoptosis markers P53, Bcl-2 and TNF-α in patients with IPA.Materials and methods: One hundred and twenty-seven patients with IPA (38 men, 89 women) were observed, among them 65 (51.2%) with microadenoma and 62 (48.8%) with macroadenoma/ patients were at the age from 35 till 60 years.Patients with pituitar...

Aim: To evaluate influence of cabergoline on LAO and BAS processes in treatment of patients with NFPA.Materials and methods: We included 64 patients with NFPA in the study. Mean age was 43.6±3.84 years (range 30–55 years). Of 64 patients 26 (40.6%) were men and 38 (59.4%) were women. Duration of the disease from diagnosis based on MRI constituted 1–15 years. Severity criteria used in the evaluation were LH, FSH and prolactin (PRL) growth a...